| Graham Chapman |
Wise Man #2/Brian Cohen/Biggus Dickus |
| John Cleese |
Wise Man #1/Reg/Jewish Official/Centurion/Deadly Dirk/Arthur |
| Terry Gilliam |
Man Even Further Forward/Revolutionary/Jailer/Blood & Thunder Prophet/Frank/Audience Member/Crucifee |
| Eric Idle |
Mr. Cheeky/Stan /Harry the Haggler/Culprit Woman/Warris/Intensely Dull Youth/Jailer's Assistant/Otto/Lead Singer Crucifee |
| Terry Jones |
Mandy Cohen/Colin/Simon the Holy Man/Bob Hoskins/Saintly Passer-by/Alarmed Crucifixion Assistant |
| Michael Palin |
Wise Man #3/Mr. Big Nose/Francis/Mrs. A/Ex-Leper/Announcer/Ben/Pontius Pilate/Boring Prophet/Eddie/Shoe Follower/Nisus Wettus |
| Terence Bayler |
Gregory |
| Carol Cleveland |
Mrs. Gregory |
| Kenneth Colley |
Jesus |
| Neil Innes |
A weedy Samaritan |
| Charles McKeown |
False Prophet/Blind Man/Giggling Guard/Stig |
| John Young |
Matthias, Son of Deuteronomy of Gath |
| Gwen Taylor |
Mrs. Big Nose |
| Sue Jones-Davies |
Judith |
| Peter Brett |
|
Brian is born on the original Christmas, in the stable next door. He spends his life being mistaken for a messiah.